| Title | Job | Year |
| Family Guy COVID-19 Vaccine Awareness PSA | Peter / Stewie / Brian / Dr. Hartman (voice) | 2021 Try Prime Free > |
| Peacock Presents: The At-Home Variety Show Featuring Seth MacFarlane | Self - Host | 2020 Try Prime Free > |
| The Orville | Capt. Ed Mercer | 2017 Free Watch now |
| Logan Lucky | Max Chilblain | 2017 Free Watch now |
| Gwen Stefanie | You Make It Feel Like Christmas | Self | 2017 Try Prime Free > |
| Sing | Mike (voice) | 2016 Free Watch now |
| Ted 2 | Ted (voice) | 2015 Free Watch now |
| A Million Ways to Die in the West | Albert Stark | 2014 Free Watch now |
| Movie 43 | 2013 Free Watch now | |
| Ted | Ted (voice) | 2012 Free Watch now |
| Seth MacFarlane: Swingin' in Concert | Himself | 2011 Try Prime Free > |
| Family Guy Presents: It's a Trap! | Peter Griffin as Han Solo / Stewie Griffin as Darth Vader / Brian Griffin as Chewbacca / Glenn Quagmire as C-3PO / Carter Pewterschmidt as Emperor Palpatine / Roger as Moff Jerjerrod / Tim the Bear as Wickett / Live Studio Ostrich / Pee-wee Herman (voice) | 2010 Try Prime Free > |
| Comedy Central Roast of Donald Trump | Self | 2011 Free Watch now |
| Tooth Fairy | Ziggy | 2010 Free Watch now |
| The Drawn Together Movie: The Movie! | I.S.R.A.E.L. (aka Intelligent Smart Robotic Animated Eraser Lady) (voice) | 2010 Try Prime Free > |
| Robot Chicken: Star Wars Episode III | Emperor Palpatine (voice) | 2010 Try Prime Free > |
| Comedy Central Roast of David Hasselhoff | Self - Roastmaster | 2010 Free Watch now |
| The Simpsons 20th Anniversary Special - In 3D! On Ice! | Himself | 2010 Try Prime Free > |
| Futurama: Into the Wild Green Yonder | 2009 Try Prime Free > | |
| Family Guy Presents: Something, Something, Something, Dark Side | Peter Griffin as Han Solo / Brian Griffin as Chewbacca / Stewie Griffin as Darth Vader / Glenn Quagmire as C-3PO / Dr. Elmer Hartman as General Rieekan / Carter Pewterschmidt as Emperor Palpatine (voice) | 2009 Try Prime Free > |
| Family Guy Presents: Seth & Alex's Almost Live Comedy Show | Self / Various (voice) | 2009 Try Prime Free > |
| Seth MacFarlane's Cavalcade of Cartoon Comedy | Various Characters (voice) | 2008 Try Prime Free > |
| Hellboy II: The Golden Army | Johann Krauss (voice) | 2008 Free Watch now |
| Robot Chicken: Star Wars Episode II | Emperor Palpatine / Dr. Ball / Figrin D'an (voice) | 2008 Try Prime Free > |
| Robot Chicken: Star Wars | Emperor Palpatine (voice) | 2007 Try Prime Free > |
| Family Guy Presents: Blue Harvest | 2007 Try Prime Free > | |
| Life Is Short | Dr. Ned | 2006 Try Prime Free > |
| American Dad! | Stan Smith / Roger (voice) | 2005 Free Watch now |
| Family Guy Presents: Stewie Griffin: The Untold Story | Stewie Griffin / Various Characters (voice) | 2005 Try Prime Free > |
| Family Guy | Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire / Tom Tucker (voice) | 1999 Free Watch now |
