UFC 271: Adesanya vs. Whittaker 2 was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on February 12, 2022 at the Toyota Center in Houston, Texas, United States. A UFC Middleweight Championship rematch between then champion Israel Adesanya and former champion Robert Whittaker (also The Ultimate Fighter: The Smashes welterweight winner) served as the event's headliner. The pairing met previously in October 2019 at UFC 243, when then interim champion Adesanya knocked out Whittaker in the second round to unify the middleweight title.

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